Un calacio, chalazión o lipogranuloma de glándula de Meibomio es un quiste en el párpado causado por la inflamación de la glándula de Meibomio obstruida, localizadas cerca de las pestañas, por lo general en el párpado superior. Un calacio se distingue de un orzuelo en que no suelen ser tan dolorosos, tienden a ser de mayor tamaño y no suelen verse acompañados por signos de flogosis, el calor despedido por la inflamación. Un calacio eventualmente desaparece al cabo de pocos meses, aunque en muchos casos, se requiere tratamiento médico, que usualmente consiste en una incisión y compresas tibias.

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Chalazion is a cyst in the eyelid due to a blocked oil gland. They are typically in the middle of the eyelid, red, and non painful. They tend to come on gradually over a few weeks. A chalazion may occur following a stye or from hardened oils blocking the gland. The blocked gland is usually the meibomian gland but can also be the gland of Zeis. A stye and cellulitis may appear similar. A stye; however, is usually more sudden in onset, painful, and occurs at the edge of the eyelid. Cellulitis is also typically painful. Treatment is typically initially with warm compresses. If this is not effective injecting steroids into the lesion maybe tried. If large incision and drainage maybe recommended. While relatively common the frequency of the condition is unknown. The term is from the Greek "khalazion" meaning "small hailstone".

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