Se denomina fibrilación ventricular al trastorno del ritmo cardiaco que presenta un ritmo ventricular rápido (más de 250 latidos por minuto), irregular, de morfología caótica y que lleva irremediablemente a la pérdida total de la contracción cardíaca, con una falta total del bombeo sanguíneo y por tanto a la muerte del paciente.

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Ventricular fibrillation (V-fib or VF) is when the heart quivers instead of pumps due to disorganized electrical activity in the ventricles. It results in cardiac arrest with loss of consciousness and no pulse. This is followed by irreversible death without treatment. Ventricular fibrillation is found initially in about 10% of people in cardiac arrest. Ventricular fibrillation can occur due to coronary heart disease, valvular heart disease, cardiomyopathy, Brugada syndrome, long QT syndrome, or intracranial hemorrhage. Diagnosis is by an electrocardiogram (ECG) showing unformed QRS complexes without any clear P waves. An important differential diagnosis is torsades de pointes. Treatment is with cardiopulmonary resuscitation (CPR) and defibrillation. Biphasic defibrillation may be better than monophasic. The medication epinephrine or amiodarone may be given if initial treatments are not effective. Rates of survival are about 46%.

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