Un microbio (del griego científico μικρόβιος [microbios]; de μικρός [micrós], "pequeño", y βίος [bíos], ‘vida’; ser vivo diminuto), también llamado microorganismo, es un ser vivo, o un sistema biológico, que solo puede visualizarse con el microscopio. La ciencia que estudia los microorganismos es la microbiología. Son organismos dotados de individualidad que presentan, a diferencia de las plantas y los animales, una organización biológica elemental. El concepto de microorganismo es operativo y carece de cualquier implicación taxonómica o filogenética dado que engloba organismos unicelulares y pluricelulares no relacionados evolutivamente entre sí, tanto procariotas (como las bacterias), como eucariotas (como los protozoos), una parte de las algas y los hongos, e incluso entidades biológicas acelulares de tamaño ultramicroscópico, como los virus o los priones. Estos últimos generalmente no son considerados seres vivos y por lo tanto no son microorganismos en sentido estricto; no obstante, también están incluidos en el campo de estudio de la microbiología. Los microbios tienen múltiples formas y tamaños. Si un virus de tamaño promedio tuviera el tamaño de una pelota de tenis, una bacteria sería del tamaño de media cancha de tenis y una célula eucariota sería como un estadio entero de fútbol.[cita requerida] Algunos microorganismos son patógenos y causan enfermedades a personas, animales y plantas, algunas de las cuales han sido un azote para la humanidad desde tiempos inmemoriales. No obstante, la inmensa mayoría de los microbios no son en absoluto perjudiciales y bastantes juegan un papel clave en la biosfera al proporcionar oxígeno (algas y cianobacterias), y, otros, descomponer la materia orgánica, mineralizarla y hacerla de nuevo accesible a los productores, cerrando el ciclo de la materia.

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A microorganism or microbe is a microscopic living organism, which may be single-celled or multicellular. The study of microorganisms is called microbiology, a subject that began with the discovery of microorganisms in 1674 by Antonie van Leeuwenhoek, using a microscope of his own design. Microorganisms are very diverse and include all bacteria, archaea and most protozoa. This group also contains some species of fungi, algae, and certain microscopic animals, such as rotifers. Many macroscopic animals and plants have microscopic juvenile stages. Some microbiologists also classify viruses (and viroids) as microorganisms, but others consider these as nonliving. In July 2016, scientists reported identifying a set of 355 genes from the last universal common ancestor of all life, including microorganisms, living on Earth. Microorganisms live in every part of the biosphere, including soil, hot springs, "seven miles deep" in the ocean, "40 miles high" in the atmosphere and inside rocks far down within the Earth's crust (see also endolith). Microorganisms, under certain test conditions, have been observed to thrive in the vacuum of outer space. According to some estimates, microorganisms outweigh "all other living things combined thousands of times over". The mass of prokaryote microorganisms — which includes bacteria and archaea, but not the nucleated eukaryote microorganisms — may be as much as 0.8 trillion tons of carbon (of the total biosphere mass, estimated at between 1 and 4 trillion tons). On 17 March 2013, researchers reported data that suggested microbial life forms thrive in the Mariana Trench. the deepest spot in the Earth's oceans. Other researchers reported related studies that microorganisms thrive inside rocks up to 580 m (1,900 ft; 0.36 mi) below the sea floor under 2,590 m (8,500 ft; 1.61 mi) of ocean off the coast of the northwestern United States, as well as 2,400 m (7,900 ft; 1.5 mi) beneath the seabed off Japan. On 20 August 2014, scientists confirmed the existence of microorganisms living 800 m (2,600 ft; 0.50 mi) below the ice of Antarctica. According to one researcher, "You can find microbes everywhere — they're extremely adaptable to conditions, and survive wherever they are." Microorganisms are crucial to nutrient recycling in ecosystems as they act as decomposers. As some microorganisms can fix nitrogen, they are a vital part of the nitrogen cycle, and recent studies indicate that airborne microorganisms may play a role in precipitation and weather. Microorganisms are also exploited in biotechnology, both in traditional food and beverage preparation, and in modern technologies based on genetic engineering. A small proportion of microorganisms are pathogenic, causing disease and even death in plants and animals.

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