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Meaning
  1. 1
    English · JMdict
    antipyretic;antifebrile
  2. 2
    English · Wikipedia

    Antipyretics (/ænti.paɪˈrɛ.tɪks/, from anti- 'against' and pyretic 'feverish') are substances that reduce fever. Antipyretics cause the hypothalamus to override a prostaglandin-induced increase in temperature. The body then works to lower the temperature, which results in a reduction in fever. Most antipyretic medications have other purposes. The most common antipyretics in the United States are ibuprofen and aspirin, which are non-steroidal anti-inflammatory drugs (NSAIDs) used primarily as analgesics (pain relievers), but which also have antipyretic properties; and acetaminophen (paracetamol), an analgesic with weak anti-inflammatory properties. There is some debate over the appropriate use of such medications, as fever is part of the body's immune response to infection. A study published by the Royal Society claims fever suppression causes at least 1% more influenza cases of death, which would result in at least 700 extra deaths per year in the United States alone.

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