shirabe.org
Settings
English
Meaning
  1. 1
    JMdict
    tumor necrosis factor (e.g. cachexin);tumour necrosis factor;TNF
  2. 2
    Wikipedia

    The tumor necrosis factor (TNF) superfamily refers to a group of cytokines that can cause cell death (apoptosis). The first two members of the family to be identified were: \n* Tumor necrosis factor (TNF), formerly known as TNFα or TNF alpha, is the best-known member of this class. TNF is a monocyte-derived cytotoxin that has been implicated in tumor regression, septic shock, and cachexia. The protein is synthesized as a prohormone with an unusually long and atypical signal sequence, which is absent from the mature secreted cytokine. A short hydrophobic stretch of amino acids serves to anchor the prohormone in lipid bilayers. Both the mature protein and a partially processed form of the hormone can be secreted after cleavage of the propeptide. \n* Lymphotoxin-alpha, formerly known as Tumor necrosis factor-beta (TNF-β), is a cytokine that is inhibited by interleukin 10.

    Read full article on Wikipedia · CC-BY-SA

Save this word to start reviewing it with spaced repetition. Save word

Grammar codex

What the coloured tags mean

Hiragana

ひらがな

The rounded, flowing kana. Hiragana writes native Japanese words, grammar endings, and anything without (or alongside) kanji — it's the first script you learn. Each character stands for one syllable.

Example

ねこ — cat