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Meaning
  1. 1
    English · JMdict
    cytoskeleton
  2. 2
    English · Wikipedia

    The structure, function and dynamic behaviour of the cytoskeleton can be very different, depending on organism and cell type. Even within one cell the cytoskeleton can change through association with other proteins and the previous history of the network. There is a multitude of functions that the cytoskeleton can perform. Primarily, it gives the cell shape and mechanical resistance to deformation, and through association with extracellular connective tissue and other cells it stabilizes entire tissues. The cytoskeleton can also actively contract, thereby deforming the cell and the cell's environment and allowing cells to migrate. Moreover, it is involved in many cell signaling pathways, in the uptake of extracellular material (endocytosis), segregates chromosomes during cellular division, is involved in cytokinesis (the division of a mother cell into two daughter cells), provides a scaffold to organize the contents of the cell in space and for intracellular transport (for example, the movement of vesicles and organelles within the cell); and can be a template for the construction of a cell wall. Furthermore, it forms specialized structures, such as flagella, cilia, lamellipodia and podosomes. A large-scale example of an action performed by the cytoskeleton is muscle contraction. During contraction of a muscle, within each muscle cell, myosin molecular motors collectively exert forces on parallel actin filaments. This action contracts the muscle cell, and through the synchronous process in many muscle cells, the entire muscle.

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