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Meaning
  1. 1
    English · JMdict
    medicine myocarditis
  2. 2
    English · Wikipedia

    Myocarditis, also known as inflammatory cardiomyopathy, is inflammation of the heart muscle. The consequences of myocarditis vary widely. It can cause a mild disease without any symptoms that resolves itself, or it may cause chest pain, heart failure, or sudden death. An acute myocardial infarction-like syndrome with normal coronary arteries has a good prognosis. Heart failure, even with a dilated left ventricle, may have a good prognosis. Ventricular arrhythmias and high-degree heart block have a poor prognosis. Loss of right ventricular function is a strong predictor of death. Myocarditis is most often due to an infection by common viruses, such as parvovirus B19. Less commonly nonviral infections such as Lyme disease or Trypanosoma cruzi, or as a hypersensitivity response to drugs may be the cause. Myocarditis can sometimes be an autoimmune disease. Streptococcal M protein and coxsackievirus B have regions that are similar to the myosin protein found in the heart muscle. During and after the infection, the immune system may attack cardiac myosin. Myocarditis may include death of heart tissue. It may include dilated cardiomyopathy. A definitive diagnosis requires a heart biopsy. In 2013, about 1.5 million cases of acute myocarditis occurred. Cardiomyopathy, including myocarditis, resulted in 443,000 deaths in 2013 up from 294,000 in 1990.

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